Issue 3701, which is scheduled to be in Member's mailbox about the end of February, will have an article that I wrote on routes to La Crosse. It outlines several choices if coming from the East, and as well as SE USA. For those Members from the South and West, I did not leave you out, and gave some suggestions there also. It all depends on the time you would like to spend on the road, as well as riding or hauling.
The same article also gives some ideas for people that would like to spend some extra time in Minnesota and Wisconsin, that may be too far away to make it one day ride from La Crosse. Most of the routes and places to visit we have been there and are familiar with and make for good riding and or site-seeing.
It looks like there are many people that have not been to the La Crosse area, and are excited to go to La Crosse. Well, you will enjoy the riding. It is different from any place you have probably ever ridden before. One of the things I like about the area, is you can ride some twisty sections for an hour or so, and then turn on a road and have some more relaxing road that is preferred for big cruiser type bikes. It never gets boring.